Luteinising hormone releasing hormone (LHRH) agonists for the treatment of relapsed epithelial ovarian cancer
نویسندگان
چکیده
منابع مشابه
Luteinising hormone releasing hormone for incomplete descent of the testis.
Forty boys with 54 incompletely descended testes took part in a double blind, controlled trial of intranasal luteinising hormone releasing hormone. In the control (placebo) group of 18 boys there was no significant change in testicular descent and all required orchidopexy; in the 22 treated boys, however, 12 of 29 testes (42%) were found in a lower position. This study supports the idea that a ...
متن کاملTreating relapsed epithelial ovarian cancer with luteinizing hormone-releasing agonist (goserelin) after failure of chemotherapy.
BACKGROUND The treatment of patients with recurrent ovarian carcinoma after failure of first and second-line chemotherapy is still debated. Chemical agents used for third and fourth-line therapy usually yield poor results with severe toxic side effects. OBJECTIVE To summarize our experience with goserelin in the treatment of patients with recurrent ovarian cancer. METHODS From September 199...
متن کاملInduction of ovulation with pulsatile luteinising hormone releasing hormone.
Ovulation was successfully induced with luteinising hormone releasing hormone in 28 women with hypothalamic amenorrhoea who had failed to respond to treatment with clomiphene. Luteinising hormone releasing hormone was administered in a pulsatile manner with miniaturised automatic infusion systems. The rate of ovarian follicular maturation, as monitored by serial pelvic ultrasonography, was simi...
متن کاملResponsiveness of rat pituitary gland in vitro to pulsatile luteinising hormone-releasing hormone(LHRH) during the oestrous cycle.
Anterior pituitary gland fragments removed from female rats at various days of the oestrous cycle were perifused into small Biogel columns. After 2 hours stabilisation, the tissues were exposed at the beginning of each of five hours of perifusion to a volley of six 1-mi pulses of LHRH (10M1 8, given 4 min.apart. Pituitary glands removed during oestrus or met-oestrus showed little change in the ...
متن کاملPreparation and characterization of luteinising-hormone releasing hormone nanoliposomal microbubbles specifically targeting ovarian cancer cells in vitro.
The aim of the present study was to prepare luteinizing-hormone releasing hormone (LHRH) nanoliposomal microbubbles specifically targeting ovarian cancer cells. The lyophilization/sonication method was used to prepare non-targeting nanoliposomal microbubbles (N-N-Mbs). Using the biotin-avidin bridge method, conjugated LHRH antibodies to N-N-Mbs generated LHRH nanoliposomal microbubbles (LHRH-N-...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2016
ISSN: 1465-1858
DOI: 10.1002/14651858.cd011322.pub2